Native code may be disabled with large gem TOC

With a very large temporary object cache, the memory offset may exceed
32bits on Darwin. In this case, native code will be disabled and the session
will run without native code (as in GS64 2.x). A message is written to
stdout (either the gem log or the linked session output).

Workaround:

We do not recommend running large Gem caches on the Macintosh.